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What is⁠ Tirzepatide and How Can it Benefit You?

By Kristie Cyrus DCNP: Lets Age Gracefully!

Tirzepatide

Introduction to Peptide Therapy

Peptides are short chains of amino acids, and these amino acids are revolutionizing modern healthcare by harnessing the power of amino acids, to positively influence and regulate bodily functions. Peptides are your bodies communication tool for hormone and metabolic management. The therapeutic potential of peptides is vast, ranging from hormonal balance to metabolic regulation.

Tirzepatide

Understanding Tirzepatide: An Overview​

Tirzepatide, a novel peptide, has emerged as a promising player in the field of peptide therapy. Its unique properties make it a focal point of research and medical attention. Tirzepatide works at the molecular level, exerting its effects on the body by action on the glucagon-like peptide 1 (GLP-1) receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor which are natural incretin hormones. It’s not our goal to use big words to introduce this peptide. Simply put, GLP-1 and GIP receptors help to regulate insulin sensitivity in the body and slow gastric movement in the gut. In the brain, GLP-1 and GIP receptors regulate appetite. When the receptors are stimulated in our brain our brain “believes” we are “full”. As a result, this powerful peptide has demonstrated its ability to decrease food intake and help with fat utilization. Its These mechanisms that are garnering worldwide attention.

Biological Impact

Weight Loss!! The biological cost of obesity is well documented so significant weight loss has significant impact. Additionally, the indirect positive impacts have, frankly, astounded. It has been observed to increase heart function in obese people with lower cardiac output, diminish obstructive sleep apnea (OSA), and decrease non-alcoholic steatohepatitis or NASH (Fatty Liver), decrease drug cravings and much more. The overall mitigation of cardiovascular disease with Tirzepatide may be of great importance to those desiring weight loss that have a concurrent family history heart attack and/or stroke.

Metabolic Syndrome is defined by the presence of at least three of five medical conditions: excess abdominal fat, hypertension, high blood sugar, elevated triglycerides, and low high-density lipoproteins (HDL). Metabolic syndrome is associated with the higher risk of cardiovascular disease and diabetes. In the U.S., about 25% of the adult population has metabolic syndrome and that percentage increases with age.  GLP’s like Tirzepatide act directly to resolve these issues thus causing the patient to recover from the presence of Metabolic Syndrome. Recovery from Metabolic Syndrome dramatically extends a healthy life. At Cyrus Cosmetics, we believe this drug class (GLP-1’s and GIP’s) are the most important pharmacological contribution to human health since penicillin.

Clinical Trials and Research Findings

Besides controlling blood sugar, Tirzepatide use resulted in weight loss. Pharma companies created specific formulations to help patients shed pounds. In 2022, a phase 3 randomized, controlled clinical trial demonstrated that Tirzepatide led to a 20% reduction in body weight over 72 weeks. Multiple, well accepted clinical trials have affirmed this weight loss has been consistently achieved in patients receiving the peptide therapy.

Peptide Hormone Therapy Integration and Disadvantages of GLP-1’s

Combining Tirzepatide with other peptide hormones achieves synergistic effects, resulting in positive outcomes and health benefits. However, there are documented disadvantages of GLP-1’s and GIP hormone agonists. These drug classes slow gastric emptying thus prolonging the feeling of fullness. So, it stands to reason the negative side effects are demonstrated when these effects are too pronounced. These effects include nausea, vomiting, and while small: an increased risk of pancreatitis, gastroparesis, and bowel obstruction. It should be noted these issues are particularly observed in diabetic patients not non-diabetic weight loss patients. As a result of these potential side effects, at Cyrus Cosmetics, we observe an approach to maximize wellness and minimize the chance for side effects:

  1. Take the lowest effective dose that modulates hunger and “food noise” (the goal isn’t to get to 15mg weekly for diabetic management but rather healthy weight loss).
  2. Evaluate blood tests that may contribute to poor energy output and activity like Niacin and B vitamins and rectify.
  3. Human Growth Hormone stimulating peptides (like CJC-1295/Ipamorelin: Reparative peptides) to raise, naturally, growth hormone that diminish with age. Healthy amounts of HGH hormone directly lead to optimized lipid utilization, lean muscle development and increased energy that all lead to better exercise capacity.
  4. Utilization of anti-inflammatory nutraceuticals such as NAD and Glutathione that raise energy levels, decrease inflammation, increases focus, exercise capacity and immune health. Sometimes we just need a kick-start!

5. Checking testosterone in both men and women is a useful addition to our process. At Cyrus Cosmetics, we don’t prescribe testosterone but this can be checked and corrected with your primary doctor or urologist.

Personalized Peptide Therapy

Tirzepatide allows for tailored treatment plans, contributing to the concept of personalized medicine and improving patient outcomes. Viewing the human being holistically leads to better outcomes and fewer or zero downsides. At Cyrus Cosmetics it’s about wellness not the “look good Olympics”. If we feel better, we will look better and be better partners in relationships at work and home. We will be more positive about our lives. A positive snowball effect: Lets Age Gracefully!

Conclusion

Tirzepatide stands at the forefront of peptide therapy, showcasing remarkable potential across various medical domains. As research advances, Tirzepatide is poised to shape the future of peptide therapies, leading to a paradigm shift in the landscape of healthcare. Goodbye to weak will and hello to wellness!

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